close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS17895.1PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: pna:Pnap_3244 peptidase S1 and S6, chymotrypsin/Hap. (330 aa)    
Predicted Functional Partners:
ACS18047.1
PFAM: Anti sigma-E protein RseA family protein; KEGG: dia:Dtpsy_2626 anti sigma-E protein, RseA.
  
 
 0.793
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.723
ACS17893.1
PFAM: protein of unknown function DUF58; KEGG: pol:Bpro_3892 protein of unknown function DUF58.
 
     0.684
ACS17894.1
Sigma 54 interacting domain protein; PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: pol:Bpro_3891 ATPase associated with various cellular activities, AAA_3.
       0.650
ACS17171.1
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: azo:azo3438 putative virulence regulator protein.
 
  
 0.619
ACS17371.1
PAS/PAC sensor hybrid histidine kinase; KEGG: scl:sce0929 two-component hybrid sensor and regulator; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
  
  
 0.611
ACS17896.1
PFAM: TatD-related deoxyribonuclease; KEGG: pol:Bpro_3885 TatD-related deoxyribonuclease.
     
 0.602
def-2
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
 
  
 0.580
ACS17892.1
PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: pol:Bpro_3893 von Willebrand factor, type A.
 
  
 0.568
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
  
 0.558
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.