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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS18028.1PFAM: HemY domain protein; KEGG: aav:Aave_1996 HemY domain-containing protein. (427 aa)    
Predicted Functional Partners:
ACS18027.1
PFAM: protein of unknown function DUF513 hemX; KEGG: vei:Veis_1038 protein of unknown function DUF513, HemX.
  
 0.990
ACS18026.1
Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
   
 0.899
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 0.875
ACS20954.1
KEGG: pol:Bpro_1295 putative lipoprotein.
 
     0.790
ACS19715.1
KEGG: vei:Veis_3631 hypothetical protein.
 
   
 0.777
ACS18946.1
KEGG: rfr:Rfer_2901 putative inner membrane transmembrane protein.
  
     0.766
ACS20740.1
KEGG: aav:Aave_3642 hypothetical protein.
  
     0.764
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
    0.764
ACS21894.1
PFAM: protein of unknown function DUF1239; KEGG: aav:Aave_4783 hypothetical protein.
  
     0.760
ACS17255.1
KEGG: aav:Aave_4527 putative proline rich signal peptide protein.
  
     0.757
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
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