close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS18114.1PFAM: isochorismatase hydrolase; KEGG: aav:Aave_1968 isochorismatase hydrolase. (194 aa)    
Predicted Functional Partners:
ACS18112.1
Transcriptional regulator, AraC family; PFAM: ThiJ/PfpI domain protein; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: aav:Aave_1966 AraC family transcriptional regulator.
 
    0.953
ACS18113.1
PFAM: ThiJ/PfpI domain protein; KEGG: rfr:Rfer_2521 ThiJ/PfpI.
 
    0.861
ACS20038.1
PFAM: isochorismatase hydrolase; KEGG: vfm:VFMJ11_A0729 isochorismatase hydrolase.
  
     0.674
ACS18115.1
KEGG: dia:Dtpsy_2422 hypothetical protein.
  
    0.534
ACS17151.1
PFAM: isochorismatase hydrolase; KEGG: bxe:Bxe_A0706 putative isochorismatase hydrolase.
  
     0.480
purM
KEGG: pol:Bpro_3566 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
       0.446
ACS20729.1
KEGG: pna:Pnap_0914 hypothetical protein.
 
    0.435
ACS17164.1
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
 
 0.411
ACS18655.1
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
 
 0.411
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
    0.401
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (34%) [HD]