close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS18284.1KEGG: rfr:Rfer_2980 putative signal peptide protein. (168 aa)    
Predicted Functional Partners:
ACS18285.1
Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: pol:Bpro_1809 signal transduction histidine kinase, nitrogen specific, NtrB.
       0.861
ACS18052.1
KEGG: pol:Bpro_3636 putative transmembrane protein.
  
     0.768
ACS19382.1
KEGG: pna:Pnap_2002 hypothetical protein.
  
     0.765
ACS18281.1
KEGG: ajs:Ajs_1187 putative transmembrane protein.
 
     0.746
ACS21229.1
PFAM: CheW domain protein; KEGG: pol:Bpro_1138 CheW-like protein.
  
     0.729
ACS17558.1
KEGG: pol:Bpro_1065 hypothetical protein.
  
     0.717
ACS18028.1
PFAM: HemY domain protein; KEGG: aav:Aave_1996 HemY domain-containing protein.
 
     0.717
ACS20951.1
KEGG: pol:Bpro_1298 hypothetical protein.
  
     0.714
ntrC
Nitrogen metabolism transcriptional regulator, NtrC, Fis Family; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
       0.707
ACS18027.1
PFAM: protein of unknown function DUF513 hemX; KEGG: vei:Veis_1038 protein of unknown function DUF513, HemX.
 
     0.702
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (28%) [HD]