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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS18317.1KEGG: bja:bll4496 hypothetical protein. (124 aa)    
Predicted Functional Partners:
ACS18315.1
KEGG: rpb:RPB_2704 nitrile hydratase, alpha subunit; TIGRFAM: nitrile hydratase, alpha subunit; PFAM: Nitrile hydratase alpha chain.
 
   
 0.955
ACS18316.1
Nitrile hydratase; NHase catalyzes the hydration of various nitrile compounds to the corresponding amides; Belongs to the nitrile hydratase subunit beta family.
 
   
 0.955
ACS18747.1
Nitrile hydratase; NHase catalyzes the hydration of various nitrile compounds to the corresponding amides; Belongs to the nitrile hydratase subunit beta family.
 
   
 0.812
ACS18746.1
KEGG: bcm:Bcenmc03_3233 nitrile hydratase, alpha subunit; TIGRFAM: nitrile hydratase, alpha subunit; PFAM: Nitrile hydratase alpha chain.
 
   
 0.811
ACS21029.1
PFAM: ferredoxin; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: dac:Daci_5738 adenylate/guanylate cyclase.
  
     0.706
ACS17718.1
PFAM: major facilitator superfamily MFS_1; KEGG: pol:Bpro_3401 major facilitator superfamily MFS_1.
  
     0.612
ACS18312.1
KEGG: hypothetical protein.
       0.575
ACS18313.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.575
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.575
ACS19860.1
KEGG: bxe:Bxe_B1808 hypothetical protein.
 
     0.464
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
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