close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS18424.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: pna:Pnap_1622 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (328 aa)    
Predicted Functional Partners:
ACS21322.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: aav:Aave_4350 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
 
  
 0.948
ACS20535.1
Hydroxypyruvate reductase; PFAM: MOFRL domain protein; KEGG: ajs:Ajs_1122 hydroxypyruvate reductase.
 
 0.944
ACS20031.1
PFAM: PfkB domain protein; KEGG: pol:Bpro_1737 PfkB.
 
 
 0.938
ACS19526.1
PFAM: aminotransferase class V; KEGG: dac:Daci_3052 serine--glyoxylate transaminase.
  
 
 0.925
ACS22706.1
TIGRFAM: gluconate kinase; PFAM: carbohydrate kinase FGGY; KEGG: sugar kinase; K00851 gluconokinase; Belongs to the FGGY kinase family.
 
 
 0.920
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.918
ACS21833.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: pol:Bpro_0422 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
 
  
0.917
ACS16885.1
PFAM: FAD linked oxidase domain protein; KEGG: aav:Aave_0645 FAD linked oxidase domain-containing protein.
   
 0.915
ACS16886.1
PFAM: FAD linked oxidase domain protein; KEGG: dac:Daci_0304 FAD linked oxidase domain-containing protein.
   
 0.915
ACS22222.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pol:Bpro_0053 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
 
  
0.915
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.