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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS18619.1PFAM: heat shock protein Hsp20; KEGG: lch:Lcho_3376 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. (139 aa)    
Predicted Functional Partners:
ACS18620.1
PFAM: heat shock protein Hsp20; KEGG: lch:Lcho_3375 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.
 
    
0.826
ACS16863.1
Type VI secretion ATPase, ClpV1 family; KEGG: bpt:Bpet4107 putative ATPase with chaperone activity; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.
  
 
 0.690
ACS17193.1
Type VI secretion ATPase, ClpV1 family; KEGG: azo:azo3903 putative ATP-dependent Clp protease, ATP-binding subunit ClpB; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.
  
 
 0.690
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.690
ACS19276.1
KEGG: pol:Bpro_2940 ATPase AAA-2; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.
  
 
 0.690
ACS18617.1
KEGG: har:HEAR2529 hypothetical protein.
 
  
 0.675
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 
 0.674
ACS18616.1
PFAM: Erythromycin esterase; KEGG: met:M446_2872 erythromycin esterase.
 
  
 0.662
ACS18618.1
Hypothetical protein.
       0.625
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.558
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
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