Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACS18662.1PFAM: NUDIX hydrolase; KEGG: pna:Pnap_2817 NUDIX hydrolase. (183 aa)    
Predicted Functional Partners:
ACS18661.1
PFAM: CreA family protein; KEGG: eba:ebA3483 CreA protein.
       0.806
ACS18663.1
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: pol:Bpro_2124 fumarylacetoacetate (FAA) hydrolase.
       0.798
ACS18664.1
KEGG: pol:Bpro_2136 maleylacetoacetate isomerase; TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase domain.
       0.676
ACS18665.1
PFAM: protein of unknown function DUF152; KEGG: pol:Bpro_2137 protein of unknown function DUF152; Belongs to the multicopper oxidase YfiH/RL5 family.
       0.615
bpt
Arginyltransferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.
     
 0.591
ACS18660.1
PFAM: Peptidase M23; KEGG: aav:Aave_1416 peptidase M23B.
       0.531
ACS18128.1
PFAM: NUDIX hydrolase; KEGG: dac:Daci_5341 NUDIX hydrolase.
  
  
 0.485
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.412
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
     
 0.411
ACS17948.1
PFAM: NUDIX hydrolase; KEGG: vei:Veis_1027 NUDIX hydrolase.
 
   
0.408
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
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