close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dctASodium:dicarboxylate symporter; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (447 aa)    
Predicted Functional Partners:
ACS20562.1
PFAM: sodium:dicarboxylate symporter; KEGG: dac:Daci_0237 C4-dicarboxylate transporter DctA; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
  
  
 
0.903
dctA-2
Sodium:dicarboxylate symporter; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
  
  
 
0.900
ACS18678.1
PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; KEGG: pol:Bpro_2149 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.642
ACS18080.1
TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; KEGG: pol:Bpro_3601 succinate dehydrogenase subunit D.
   
  
 0.598
ACS18676.1
TIGRFAM: acetoacetyl-CoA reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: rfr:Rfer_2560 3-ketoacyl-(acyl-carrier-protein) reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.531
ACS22209.1
KEGG: vei:Veis_2514 hypothetical protein.
   
  
 0.528
ACS20738.1
PFAM: Na+/solute symporter; KEGG: dac:Daci_5457 Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.443
ACS17803.1
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: aav:Aave_1008 glutamate synthase (NADH) large subunit.
     
 0.441
ACS21415.1
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
  
 0.435
ACS20596.1
PFAM: carbon starvation protein CstA; KEGG: aav:Aave_4228 carbon starvation protein CstA.
  
  
 0.402
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (20%) [HD]