| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACS18762.1 | ACS18766.1 | Vapar_2127 | Vapar_2131 | methylmalonyl-CoA mutase, large subunit; KEGG: pol:Bpro_2161 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | 0.866 |
| ACS18762.1 | ACS18768.1 | Vapar_2127 | Vapar_2133 | methylmalonyl-CoA mutase, large subunit; KEGG: pol:Bpro_2161 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. | KEGG: rfr:Rfer_2801 lactoylglutathione lyase. | 0.842 |
| ACS18762.1 | bioB | Vapar_2127 | Vapar_2132 | methylmalonyl-CoA mutase, large subunit; KEGG: pol:Bpro_2161 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.771 |
| ACS18766.1 | ACS18762.1 | Vapar_2131 | Vapar_2127 | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | methylmalonyl-CoA mutase, large subunit; KEGG: pol:Bpro_2161 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. | 0.866 |
| ACS18766.1 | ACS18768.1 | Vapar_2131 | Vapar_2133 | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | KEGG: rfr:Rfer_2801 lactoylglutathione lyase. | 0.868 |
| ACS18766.1 | ACS21393.1 | Vapar_2131 | Vapar_4788 | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1898 beta alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.814 |
| ACS18766.1 | ACS21802.1 | Vapar_2131 | Vapar_5200 | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; KEGG: dac:Daci_0882 biotin--acetyl-CoA-carboxylase ligase. | 0.855 |
| ACS18766.1 | bioB | Vapar_2131 | Vapar_2132 | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.825 |
| ACS18768.1 | ACS18762.1 | Vapar_2133 | Vapar_2127 | KEGG: rfr:Rfer_2801 lactoylglutathione lyase. | methylmalonyl-CoA mutase, large subunit; KEGG: pol:Bpro_2161 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. | 0.842 |
| ACS18768.1 | ACS18766.1 | Vapar_2133 | Vapar_2131 | KEGG: rfr:Rfer_2801 lactoylglutathione lyase. | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | 0.868 |
| ACS18768.1 | bioB | Vapar_2133 | Vapar_2132 | KEGG: rfr:Rfer_2801 lactoylglutathione lyase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.838 |
| ACS19430.1 | bioB | Vapar_2810 | Vapar_2132 | TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: rpi:Rpic_1371 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.941 |
| ACS19430.1 | bioD | Vapar_2810 | Vapar_2812 | TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: rpi:Rpic_1371 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.999 |
| ACS19430.1 | bioF | Vapar_2810 | Vapar_2811 | TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: rpi:Rpic_1371 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.996 |
| ACS21393.1 | ACS18766.1 | Vapar_4788 | Vapar_2131 | PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1898 beta alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | 0.814 |
| ACS21393.1 | bioB | Vapar_4788 | Vapar_2132 | PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1898 beta alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.790 |
| ACS21393.1 | bioD | Vapar_4788 | Vapar_2812 | PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1898 beta alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.802 |
| ACS21393.1 | bioF | Vapar_4788 | Vapar_2811 | PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1898 beta alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.634 |
| ACS21802.1 | ACS18766.1 | Vapar_5200 | Vapar_2131 | TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; KEGG: dac:Daci_0882 biotin--acetyl-CoA-carboxylase ligase. | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | 0.855 |
| ACS21802.1 | bioB | Vapar_5200 | Vapar_2132 | TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; KEGG: dac:Daci_0882 biotin--acetyl-CoA-carboxylase ligase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.944 |