close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS18792.1PFAM: glutaredoxin; KEGG: aav:Aave_2457 glutaredoxin. (213 aa)    
Predicted Functional Partners:
ACS17607.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.978
ACS18793.1
PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: rfr:Rfer_2208 oligopeptidase A.
  
  
 0.809
secB
Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
  
 0.788
ACS21719.1
KEGG: pol:Bpro_4643 protein of unknown function DUF1631.
  
     0.760
ACS19382.1
KEGG: pna:Pnap_2002 hypothetical protein.
  
     0.752
ACS17558.1
KEGG: pol:Bpro_1065 hypothetical protein.
  
     0.749
ACS21229.1
PFAM: CheW domain protein; KEGG: pol:Bpro_1138 CheW-like protein.
  
   
 0.734
folD
Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
    0.730
ACS18052.1
KEGG: pol:Bpro_3636 putative transmembrane protein.
 
     0.725
ACS17515.1
PFAM: ProQ activator of osmoprotectant transporter ProP; KEGG: pol:Bpro_1033 hypothetical protein.
 
     0.719
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (28%) [HD]