| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACS18765.1 | ACS18766.1 | Vapar_2130 | Vapar_2131 | PFAM: carboxyl transferase; KEGG: ajs:Ajs_2042 carboxyl transferase. | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | 0.997 |
| ACS18765.1 | ACS18805.1 | Vapar_2130 | Vapar_2170 | PFAM: carboxyl transferase; KEGG: ajs:Ajs_2042 carboxyl transferase. | TIGRFAM: propionate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: pol:Bpro_2633 propionate--CoA ligase. | 0.916 |
| ACS18765.1 | ACS19875.1 | Vapar_2130 | Vapar_3257 | PFAM: carboxyl transferase; KEGG: ajs:Ajs_2042 carboxyl transferase. | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: ajs:Ajs_2009 methylmalonate-semialdehyde dehydrogenase [acylating]. | 0.912 |
| ACS18765.1 | ACS19889.1 | Vapar_2130 | Vapar_3271 | PFAM: carboxyl transferase; KEGG: ajs:Ajs_2042 carboxyl transferase. | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: dac:Daci_0980 methylmalonate-semialdehyde dehydrogenase. | 0.912 |
| ACS18765.1 | ACS20422.1 | Vapar_2130 | Vapar_3808 | PFAM: carboxyl transferase; KEGG: ajs:Ajs_2042 carboxyl transferase. | PFAM: phosphate acetyl/butaryl transferase; KEGG: bph:Bphy_3685 phosphate butyryltransferase. | 0.901 |
| ACS18765.1 | ACS21335.1 | Vapar_2130 | Vapar_4730 | PFAM: carboxyl transferase; KEGG: ajs:Ajs_2042 carboxyl transferase. | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: pna:Pnap_0459 acyl-CoA dehydrogenase domain-containing protein. | 0.922 |
| ACS18765.1 | ACS22092.1 | Vapar_2130 | Vapar_5497 | PFAM: carboxyl transferase; KEGG: ajs:Ajs_2042 carboxyl transferase. | PFAM: CoA-binding domain protein; KEGG: bja:blr3446 6-carboxyhexanoate--CoA ligase. | 0.905 |
| ACS18765.1 | ACS22710.1 | Vapar_2130 | Vapar_6147 | PFAM: carboxyl transferase; KEGG: ajs:Ajs_2042 carboxyl transferase. | PFAM: CoA-binding domain protein; ATP-grasp domain protein; KEGG: dac:Daci_1759 CoA-binding domain-containing protein. | 0.905 |
| ACS18765.1 | acsA | Vapar_2130 | Vapar_2526 | PFAM: carboxyl transferase; KEGG: ajs:Ajs_2042 carboxyl transferase. | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.916 |
| ACS18766.1 | ACS18765.1 | Vapar_2131 | Vapar_2130 | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | PFAM: carboxyl transferase; KEGG: ajs:Ajs_2042 carboxyl transferase. | 0.997 |
| ACS18766.1 | ACS18805.1 | Vapar_2131 | Vapar_2170 | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | TIGRFAM: propionate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: pol:Bpro_2633 propionate--CoA ligase. | 0.915 |
| ACS18766.1 | ACS19875.1 | Vapar_2131 | Vapar_3257 | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: ajs:Ajs_2009 methylmalonate-semialdehyde dehydrogenase [acylating]. | 0.906 |
| ACS18766.1 | ACS19889.1 | Vapar_2131 | Vapar_3271 | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: dac:Daci_0980 methylmalonate-semialdehyde dehydrogenase. | 0.906 |
| ACS18766.1 | ACS20422.1 | Vapar_2131 | Vapar_3808 | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | PFAM: phosphate acetyl/butaryl transferase; KEGG: bph:Bphy_3685 phosphate butyryltransferase. | 0.906 |
| ACS18766.1 | ACS21335.1 | Vapar_2131 | Vapar_4730 | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: pna:Pnap_0459 acyl-CoA dehydrogenase domain-containing protein. | 0.919 |
| ACS18766.1 | ACS22092.1 | Vapar_2131 | Vapar_5497 | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | PFAM: CoA-binding domain protein; KEGG: bja:blr3446 6-carboxyhexanoate--CoA ligase. | 0.900 |
| ACS18766.1 | ACS22710.1 | Vapar_2131 | Vapar_6147 | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | PFAM: CoA-binding domain protein; ATP-grasp domain protein; KEGG: dac:Daci_1759 CoA-binding domain-containing protein. | 0.900 |
| ACS18766.1 | acsA | Vapar_2131 | Vapar_2526 | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.915 |
| ACS18805.1 | ACS18765.1 | Vapar_2170 | Vapar_2130 | TIGRFAM: propionate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: pol:Bpro_2633 propionate--CoA ligase. | PFAM: carboxyl transferase; KEGG: ajs:Ajs_2042 carboxyl transferase. | 0.916 |
| ACS18805.1 | ACS18766.1 | Vapar_2170 | Vapar_2131 | TIGRFAM: propionate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: pol:Bpro_2633 propionate--CoA ligase. | TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: aav:Aave_2515 acetyl-CoA carboxylase, biotin carboxylase. | 0.915 |