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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS18813.1SMART: helicase c2; KEGG: pol:Bpro_2617 helicase C2. (685 aa)    
Predicted Functional Partners:
ACS18878.1
PFAM: type III restriction protein res subunit; DNA primase small subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase; KEGG: tmz:Tmz1t_0307 type III restriction protein res subunit.
   
 0.936
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.928
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.921
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 0.919
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.914
ACS18812.1
PFAM: protein of unknown function DUF465; KEGG: pol:Bpro_2618 protein of unknown function DUF465.
       0.814
ACS21186.1
PFAM: metallophosphoesterase; KEGG: pna:Pnap_1662 metallophosphoesterase.
  
 0.791
ACS22484.1
PFAM: metallophosphoesterase; KEGG: bur:Bcep18194_A4597 metallophosphoesterase.
  
 0.791
ACS19477.1
KEGG: aav:Aave_3411 DNA-directed DNA polymerase.
 
 0.756
ACS22584.1
KEGG: spe:Spro_0731 DNA polymerase II; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; SMART: DNA-directed DNA polymerase B.
  
 0.734
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
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