Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACS18813.1SMART: helicase c2; KEGG: pol:Bpro_2617 helicase C2. (685 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.906
ACS18878.1
PFAM: type III restriction protein res subunit; DNA primase small subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase; KEGG: tmz:Tmz1t_0307 type III restriction protein res subunit.
   
 0.868
ACS16665.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.834
ACS18812.1
PFAM: protein of unknown function DUF465; KEGG: pol:Bpro_2618 protein of unknown function DUF465.
       0.815
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.803
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.762
ACS21401.1
PFAM: cytochrome P450; FAD-binding domain protein; flavodoxin/nitric oxide synthase; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: bja:blr2882 bifunctional P-450:NADPH-P450 reductase.
   
 0.710
ACS22584.1
KEGG: spe:Spro_0731 DNA polymerase II; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; SMART: DNA-directed DNA polymerase B.
  
 0.702
ACS21186.1
PFAM: metallophosphoesterase; KEGG: pna:Pnap_1662 metallophosphoesterase.
  
 0.682
ACS22484.1
PFAM: metallophosphoesterase; KEGG: bur:Bcep18194_A4597 metallophosphoesterase.
  
 0.682
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
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