close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS18855.1TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: dac:Daci_1543 3-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)    
Predicted Functional Partners:
ACS19879.1
3-oxoacid CoA-transferase, B subunit; KEGG: aav:Aave_3126 butyryl-CoA:acetate CoA transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase.
  
 0.913
ACS19211.1
TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: rfr:Rfer_2069 3-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 
0.912
ACS19880.1
KEGG: aav:Aave_3127 3-oxoacid CoA-transferase, A subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase.
  
 
 0.905
ACS16770.1
TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: pol:Bpro_0120 acetyl-CoA synthetase.
   
 0.904
ACS17118.1
PFAM: pyruvate carboxyltransferase; KEGG: pol:Bpro_4514 hydroxymethylglutaryl-CoA lyase.
   
 
 0.901
ACS18406.1
PFAM: pyruvate carboxyltransferase; KEGG: cti:RALTA_B2209 hydroxymethylglutaryl-CoA lyase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
   
 
 0.901
ACS19395.1
PFAM: pyruvate carboxyltransferase; KEGG: bbr:BB3124 hydroxymethylglutaryl-CoA lyase.
   
 
 0.901
ACS19885.1
PFAM: pyruvate carboxyltransferase; KEGG: dac:Daci_2875 pyruvate carboxyltransferase.
   
 
 0.901
ACS21315.1
PFAM: pyruvate carboxyltransferase; KEGG: dac:Daci_5964 pyruvate carboxyltransferase.
   
 
 0.901
ACS18854.1
PFAM: Patatin; KEGG: ajs:Ajs_1865 patatin.
 
 
 
 0.808
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (28%) [HD]