| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACS17665.1 | ACS17670.1 | Vapar_1014 | Vapar_1019 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pol:Bpro_2767 precorrin-3 methyltransferase / precorrin-6Y C5,15-methyltransferase (decarboxylating). | Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.999 |
| ACS17665.1 | ACS17671.1 | Vapar_1014 | Vapar_1020 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pol:Bpro_2767 precorrin-3 methyltransferase / precorrin-6Y C5,15-methyltransferase (decarboxylating). | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; KEGG: pol:Bpro_2775 precorrin-6Y C5,15-methyltransferase (decarboxylating); TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Protein of unknown function methylase putative. | 0.995 |
| ACS17665.1 | ACS17673.1 | Vapar_1014 | Vapar_1022 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pol:Bpro_2767 precorrin-3 methyltransferase / precorrin-6Y C5,15-methyltransferase (decarboxylating). | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: pna:Pnap_2161 precorrin-8X methylmutase CbiC/CobH. | 0.995 |
| ACS17665.1 | ACS17675.1 | Vapar_1014 | Vapar_1024 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pol:Bpro_2767 precorrin-3 methyltransferase / precorrin-6Y C5,15-methyltransferase (decarboxylating). | KEGG: pol:Bpro_2779 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | 0.999 |
| ACS17665.1 | ACS19179.1 | Vapar_1014 | Vapar_2553 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pol:Bpro_2767 precorrin-3 methyltransferase / precorrin-6Y C5,15-methyltransferase (decarboxylating). | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.668 |
| ACS17665.1 | cbiD | Vapar_1014 | Vapar_1021 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pol:Bpro_2767 precorrin-3 methyltransferase / precorrin-6Y C5,15-methyltransferase (decarboxylating). | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.977 |
| ACS17665.1 | cobD-2 | Vapar_1014 | Vapar_2555 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pol:Bpro_2767 precorrin-3 methyltransferase / precorrin-6Y C5,15-methyltransferase (decarboxylating). | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.830 |
| ACS17665.1 | cobQ | Vapar_1014 | Vapar_2565 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pol:Bpro_2767 precorrin-3 methyltransferase / precorrin-6Y C5,15-methyltransferase (decarboxylating). | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.995 |
| ACS17665.1 | cobS | Vapar_1014 | Vapar_2567 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pol:Bpro_2767 precorrin-3 methyltransferase / precorrin-6Y C5,15-methyltransferase (decarboxylating). | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.968 |
| ACS17665.1 | cobT | Vapar_1014 | Vapar_2566 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pol:Bpro_2767 precorrin-3 methyltransferase / precorrin-6Y C5,15-methyltransferase (decarboxylating). | Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.812 |
| ACS17670.1 | ACS17665.1 | Vapar_1019 | Vapar_1014 | Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pol:Bpro_2767 precorrin-3 methyltransferase / precorrin-6Y C5,15-methyltransferase (decarboxylating). | 0.999 |
| ACS17670.1 | ACS17671.1 | Vapar_1019 | Vapar_1020 | Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; KEGG: pol:Bpro_2775 precorrin-6Y C5,15-methyltransferase (decarboxylating); TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Protein of unknown function methylase putative. | 0.997 |
| ACS17670.1 | ACS17673.1 | Vapar_1019 | Vapar_1022 | Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: pna:Pnap_2161 precorrin-8X methylmutase CbiC/CobH. | 0.995 |
| ACS17670.1 | ACS17675.1 | Vapar_1019 | Vapar_1024 | Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | KEGG: pol:Bpro_2779 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | 0.998 |
| ACS17670.1 | ACS19179.1 | Vapar_1019 | Vapar_2553 | Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.696 |
| ACS17670.1 | cbiD | Vapar_1019 | Vapar_1021 | Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.990 |
| ACS17670.1 | cobD-2 | Vapar_1019 | Vapar_2555 | Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.828 |
| ACS17670.1 | cobQ | Vapar_1019 | Vapar_2565 | Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.979 |
| ACS17670.1 | cobS | Vapar_1019 | Vapar_2567 | Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.895 |
| ACS17670.1 | cobT | Vapar_1019 | Vapar_2566 | Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.804 |