close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS19255.1Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; regulatory protein Crp; KEGG: aav:Aave_3075 Crp/FNR family transcriptional regulator. (239 aa)    
Predicted Functional Partners:
ACS19254.1
PFAM: aminoglycoside phosphotransferase; KEGG: aav:Aave_3076 aminoglycoside phosphotransferase.
     
 0.803
ACS19253.1
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: aav:Aave_3077 acyl-CoA dehydrogenase domain-containing protein.
       0.689
ACS19256.1
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: pol:Bpro_2958 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
     
 0.596
ACS19257.1
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: pol:Bpro_2957 3-hydroxybutyryl-CoA dehydrogenase.
  
  
 0.536
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.534
ACS21789.1
Adenylate/guanylate cyclase with Chase sensor; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: mfa:Mfla_2129 adenylate/guanylate cyclase.
 
 0.533
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.521
ACS19420.1
Putative adenylate/guanylate cyclase; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: rfr:Rfer_2284 putative adenylate/guanylate cyclase.
 
 0.518
aqpZ
MIP family channel protein; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 0.481
ACS16771.1
Adenylate/guanylate cyclase with integral membrane sensor; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; histidine kinase HAMP region domain protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sfu:Sfum_2802 adenylate/guanylate cyclase.
 
 0.461
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.