close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS19705.1TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; KEGG: pol:Bpro_2860 aspartate kinase; Belongs to the aspartokinase family. (422 aa)    
Predicted Functional Partners:
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.992
argG
KEGG: pol:Bpro_1599 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
  
 
 0.885
ACS18481.1
PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: pol:Bpro_2190 homoserine dehydrogenase.
 
 0.874
ACS22389.1
PFAM: aminotransferase class I and II; KEGG: vei:Veis_2902 aminotransferase, class I and II.
 
 0.874
ACS22920.1
PFAM: aminotransferase class I and II; aminotransferase class V; KEGG: rso:RSp0943 aspartate aminotransferase.
 
 0.874
ACS16975.1
PFAM: aminotransferase class I and II; KEGG: rfr:Rfer_0881 aminotransferase, class I and II.
 
 0.873
ACS18482.1
KEGG: pna:Pnap_2230 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit.
  
 
 0.871
ACS20848.1
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cti:RALTA_B1800 putative pyridoxal-5'-phosphate-dependent enzyme, beta family; putative threonine synthase.
  
 
 0.871
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.856
ACS19802.1
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Beta-ketoacyl synthase; aminotransferase class-III; Acyl transferase; phosphopantetheine-binding; KEGG: bph:Bphy_1672 amino acid adenylation domain-containing protein.
  
  
 0.842
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (28%) [HD]