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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS19818.1KEGG: pna:Pnap_3192 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein. (512 aa)    
Predicted Functional Partners:
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
 
 
 0.982
ACS20341.1
Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: pol:Bpro_1639 phosphomannomutase.
 
 0.973
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: rfr:Rfer_1127 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.951
ACS18581.1
PFAM: sugar transferase; KEGG: ajs:Ajs_3034 undecaprenyl-phosphate galactose phosphotransferase.
  
  
 0.948
fbp
PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: mpt:Mpe_A2788 D-fructose 1,6-bisphosphatase.
   
 0.934
fbp-2
PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: pol:Bpro_1586 fructose-1,6-bisphosphatase.
   
 0.934
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.931
ACS18586.1
PFAM: polysaccharide biosynthesis protein CapD; Male sterility domain; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; KEGG: rfr:Rfer_2679 polysaccharide biosynthesis protein CapD.
  
  
 0.929
ACS17419.1
KEGG: pol:Bpro_3999 mannose-1-phosphate guanylyltransferase (GDP); TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; mannose-6-phosphate isomerase type II.
 
  
 
0.927
ACS17766.1
PFAM: PfkB domain protein; KEGG: dac:Daci_5591 ribokinase-like domain-containing protein.
    
 0.927
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
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