close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS19975.1PFAM: major facilitator superfamily MFS_1; nucleoside:H symporter; KEGG: reu:Reut_A1258 MFS family nucleoside/H(+) symporter. (396 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
     
 0.826
ACS19977.1
Hypothetical protein.
       0.681
ACS19648.1
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mpt:Mpe_A2785 haloacid dehalogenase.
  
  
 0.635
ACS20407.1
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rfr:Rfer_2702 HAD family hydrolase.
  
  
 0.635
ACS20658.1
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bpm:BURPS1710b_1218 putative hydrolase.
  
  
 0.635
ACS19978.1
PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: pol:Bpro_1366 hypothetical protein.
 
     0.557
ACS17799.1
PFAM: major facilitator superfamily MFS_1; KEGG: dac:Daci_3974 major facilitator transporter.
  
     0.491
ACS22384.1
PFAM: amidohydrolase 2; KEGG: pol:Bpro_0242 amidohydrolase 2.
  
     0.489
ACS21275.1
KEGG: bpy:Bphyt_2086 hypothetical protein.
  
     0.456
ACS18860.1
PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pol:Bpro_2995 radical SAM.
 
  
 0.442
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.