close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS20030.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: pna:Pnap_1485 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (328 aa)    
Predicted Functional Partners:
ACS20031.1
PFAM: PfkB domain protein; KEGG: pol:Bpro_1737 PfkB.
 
 
 0.989
ACS18344.1
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
  
 
 0.920
ACS22706.1
TIGRFAM: gluconate kinase; PFAM: carbohydrate kinase FGGY; KEGG: sugar kinase; K00851 gluconokinase; Belongs to the FGGY kinase family.
  
 
 0.908
edd
6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
    
 0.905
ACS18368.1
6-phosphogluconolactonase; KEGG: bra:BRADO5790 hypothetical protein.
   
 
  0.902
ACS22750.1
KEGG: bph:Bphy_6877 6-phosphogluconolactonase.
   
 
  0.902
ACS20032.1
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: pna:Pnap_1487 xylose isomerase domain-containing protein.
 
    0.880
ACS20029.1
Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: pna:Pnap_1493 regulatory protein, LacI.
 
  
 0.862
ACS20033.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pna:Pnap_1488 ABC transporter related.
  
    0.790
ACS20034.1
PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: pna:Pnap_1489 extracellular solute-binding protein.
       0.694
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.