node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS17406.1 | dcd | Vapar_0753 | Vapar_3880 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.757 |
ACS17607.1 | dcd | Vapar_0956 | Vapar_3880 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.605 |
ACS17607.1 | dut | Vapar_0956 | Vapar_3440 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.943 |
ACS17607.1 | ndk | Vapar_0956 | Vapar_2183 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.942 |
ACS17607.1 | pyrG | Vapar_0956 | Vapar_3443 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.485 |
ACS17607.1 | tmk | Vapar_0956 | Vapar_2858 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.961 |
ACS20493.1 | ACS20495.1 | Vapar_3879 | Vapar_3881 | PFAM: protein of unknown function zinc metallopeptidase putative; KEGG: pna:Pnap_1057 protein of unknown function, zinc metallopeptidase putative. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.409 |
ACS20493.1 | dcd | Vapar_3879 | Vapar_3880 | PFAM: protein of unknown function zinc metallopeptidase putative; KEGG: pna:Pnap_1057 protein of unknown function, zinc metallopeptidase putative. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.630 |
ACS20495.1 | ACS20493.1 | Vapar_3881 | Vapar_3879 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | PFAM: protein of unknown function zinc metallopeptidase putative; KEGG: pna:Pnap_1057 protein of unknown function, zinc metallopeptidase putative. | 0.409 |
ACS20495.1 | dcd | Vapar_3881 | Vapar_3880 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.636 |
bamE | dcd | Vapar_0407 | Vapar_3880 | SmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.610 |
coaD | dcd | Vapar_4368 | Vapar_3880 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.545 |
dcd | ACS17406.1 | Vapar_3880 | Vapar_0753 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. | 0.757 |
dcd | ACS17607.1 | Vapar_3880 | Vapar_0956 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.605 |
dcd | ACS20493.1 | Vapar_3880 | Vapar_3879 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | PFAM: protein of unknown function zinc metallopeptidase putative; KEGG: pna:Pnap_1057 protein of unknown function, zinc metallopeptidase putative. | 0.630 |
dcd | ACS20495.1 | Vapar_3880 | Vapar_3881 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.636 |
dcd | bamE | Vapar_3880 | Vapar_0407 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | SmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.610 |
dcd | coaD | Vapar_3880 | Vapar_4368 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.545 |
dcd | dut | Vapar_3880 | Vapar_3440 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.936 |
dcd | ndk | Vapar_3880 | Vapar_2183 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.941 |