| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACS18582.1 | ACS20555.1 | Vapar_1935 | Vapar_3941 | PFAM: protein of unknown function DUF201; KEGG: vpa:VP0232 putative carbamoyl phosphate synthase large subunit. | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: dac:Daci_2107 xanthine permease. | 0.819 |
| ACS18582.1 | ACS21220.1 | Vapar_1935 | Vapar_4615 | PFAM: protein of unknown function DUF201; KEGG: vpa:VP0232 putative carbamoyl phosphate synthase large subunit. | KEGG: dia:Dtpsy_2894 phosphoribosyltransferase. | 0.895 |
| ACS18582.1 | ACS22107.1 | Vapar_1935 | Vapar_5513 | PFAM: protein of unknown function DUF201; KEGG: vpa:VP0232 putative carbamoyl phosphate synthase large subunit. | KEGG: bam:Bamb_4187 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.985 |
| ACS18582.1 | carA | Vapar_1935 | Vapar_2615 | PFAM: protein of unknown function DUF201; KEGG: vpa:VP0232 putative carbamoyl phosphate synthase large subunit. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: pol:Bpro_2679 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | 0.997 |
| ACS18582.1 | carB | Vapar_1935 | Vapar_2617 | PFAM: protein of unknown function DUF201; KEGG: vpa:VP0232 putative carbamoyl phosphate synthase large subunit. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: pol:Bpro_2678 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.900 |
| ACS18582.1 | purL | Vapar_1935 | Vapar_2940 | PFAM: protein of unknown function DUF201; KEGG: vpa:VP0232 putative carbamoyl phosphate synthase large subunit. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.633 |
| ACS18582.1 | pyrB | Vapar_1935 | Vapar_4614 | PFAM: protein of unknown function DUF201; KEGG: vpa:VP0232 putative carbamoyl phosphate synthase large subunit. | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: aav:Aave_0910 aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.985 |
| ACS18582.1 | pyrD | Vapar_1935 | Vapar_2155 | PFAM: protein of unknown function DUF201; KEGG: vpa:VP0232 putative carbamoyl phosphate synthase large subunit. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.905 |
| ACS18582.1 | pyrE | Vapar_1935 | Vapar_0278 | PFAM: protein of unknown function DUF201; KEGG: vpa:VP0232 putative carbamoyl phosphate synthase large subunit. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.907 |
| ACS18582.1 | pyrF | Vapar_1935 | Vapar_5082 | PFAM: protein of unknown function DUF201; KEGG: vpa:VP0232 putative carbamoyl phosphate synthase large subunit. | KEGG: pna:Pnap_3843 orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.897 |
| ACS20555.1 | ACS18582.1 | Vapar_3941 | Vapar_1935 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: dac:Daci_2107 xanthine permease. | PFAM: protein of unknown function DUF201; KEGG: vpa:VP0232 putative carbamoyl phosphate synthase large subunit. | 0.819 |
| ACS20555.1 | ACS21220.1 | Vapar_3941 | Vapar_4615 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: dac:Daci_2107 xanthine permease. | KEGG: dia:Dtpsy_2894 phosphoribosyltransferase. | 0.897 |
| ACS20555.1 | ACS22107.1 | Vapar_3941 | Vapar_5513 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: dac:Daci_2107 xanthine permease. | KEGG: bam:Bamb_4187 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.863 |
| ACS20555.1 | carA | Vapar_3941 | Vapar_2615 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: dac:Daci_2107 xanthine permease. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: pol:Bpro_2679 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | 0.881 |
| ACS20555.1 | carB | Vapar_3941 | Vapar_2617 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: dac:Daci_2107 xanthine permease. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: pol:Bpro_2678 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.819 |
| ACS20555.1 | purL | Vapar_3941 | Vapar_2940 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: dac:Daci_2107 xanthine permease. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.803 |
| ACS20555.1 | pyrB | Vapar_3941 | Vapar_4614 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: dac:Daci_2107 xanthine permease. | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: aav:Aave_0910 aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.863 |
| ACS20555.1 | pyrD | Vapar_3941 | Vapar_2155 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: dac:Daci_2107 xanthine permease. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.844 |
| ACS20555.1 | pyrE | Vapar_3941 | Vapar_0278 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: dac:Daci_2107 xanthine permease. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.892 |
| ACS20555.1 | pyrF | Vapar_3941 | Vapar_5082 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: dac:Daci_2107 xanthine permease. | KEGG: pna:Pnap_3843 orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.894 |