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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS20572.1Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; KEGG: pna:Pnap_1010 malic enzyme. (767 aa)    
Predicted Functional Partners:
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.977
ACS19144.1
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
 
 
 0.970
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.969
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.969
ACS21089.1
KEGG: tmz:Tmz1t_1294 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 0.968
ACS21702.1
KEGG: dac:Daci_0930 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 0.968
ACS22073.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: rfr:Rfer_2799 pyruvate flavodoxin/ferredoxin oxidoreductase-like.
  
 
 0.954
ACS22072.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: rfr:Rfer_2798 2-oxoglutarate ferredoxin oxidoreductase subunit beta.
   
 0.951
ACS18466.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
  
 
 0.943
ACS18800.1
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; biotin/lipoyl attachment domain-containing protein; KEGG: pna:Pnap_1784 dihydrolipoamide dehydrogenase.
  
  
 0.942
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
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