close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS20732.1PFAM: GTP cyclohydrolase I; KEGG: pol:Bpro_0869 GTP cyclohydrolase. (243 aa)    
Predicted Functional Partners:
ACS20709.1
PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: vei:Veis_1235 putative 6-pyruvoyl tetrahydropterin synthase.
  
 
 0.984
ACS20734.1
PFAM: NUDIX hydrolase; KEGG: lch:Lcho_4015 NUDIX hydrolase.
    
 0.972
ACS18119.1
TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: rfr:Rfer_2508 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase.
 
  
 0.961
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
  
 
 0.946
ACS19250.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
  
 0.941
ACS20611.1
KEGG: pzu:PHZ_c2444 alkaline phosphatase D.
    
 0.923
ACS22250.1
KEGG: dia:Dtpsy_2905 alkaline phosphatase.
    
 0.923
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
    
 0.915
ACS20731.1
PFAM: BLUF domain protein; KEGG: pol:Bpro_0870 sensors of blue-light using FAD.
 
    0.899
ACS17626.1
PFAM: dihydroneopterin aldolase; KEGG: rfr:Rfer_0814 dihydroneopterin aldolase.
  
  
 0.897
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.