close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS20762.1PFAM: protein of unknown function DUF925; KEGG: cvi:CV_4214 hypothetical protein. (179 aa)    
Predicted Functional Partners:
ACS20761.1
PFAM: GCN5-related N-acetyltransferase; KEGG: bur:Bcep18194_B0771 GCN5-related N-acetyltransferase.
 
     0.757
ACS20764.1
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: rme:Rmet_3694 response regulator receiver domain protein (CheY-like).
  
    0.564
ACS20763.1
Chemotaxis phosphatase, CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
       0.559
ACS20760.1
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rle:RL2545 hypothetical protein.
       0.550
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
       0.506
cheD
CheD, stimulates methylation of MCP protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
       0.506
ACS20767.1
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
       0.506
ACS20768.1
Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: har:HEAR1309 hypothetical protein.
       0.496
ACS20769.1
PFAM: CheY binding; Signal transducing histidine kinase homodimeric; Hpt domain protein; CheW domain protein; ATP-binding region ATPase domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; KEGG: rme:Rmet_3689 CheA signal transduction histidine kinases.
       0.449
ACS21600.1
Putative transcriptional regulator; KEGG: bbr:BB3855 hypothetical protein.
  
     0.442
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.