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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
cheBResponse regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (359 aa)    
Predicted Functional Partners:
ACS20769.1
PFAM: CheY binding; Signal transducing histidine kinase homodimeric; Hpt domain protein; CheW domain protein; ATP-binding region ATPase domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; KEGG: rme:Rmet_3689 CheA signal transduction histidine kinases.
 
 0.999
ACS20767.1
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
  
 0.997
ACS20800.1
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: mms:mma_2094 CheW purine-binding chemotaxis protein.
 
 
 0.995
ACS20803.1
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: mms:mma_2094 CheW purine-binding chemotaxis protein.
 
 
 0.995
cheD
CheD, stimulates methylation of MCP protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  
 0.994
ACS21227.1
CheA signal transduction histidine kinase; PFAM: response regulator receiver; Hpt domain protein; Signal transducing histidine kinase homodimeric; CheW domain protein; ATP-binding region ATPase domain protein; SMART: response regulator receiver; Hpt domain protein; CheW domain protein; ATP-binding region ATPase domain protein; KEGG: pol:Bpro_1140 CheA signal transduction histidine kinases.
 
 
 0.991
ACS17341.1
PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: tbd:Tbd_1620 methyl-accepting chemotaxis sensory transducer.
 
 0.985
ACS20764.1
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: rme:Rmet_3694 response regulator receiver domain protein (CheY-like).
 
 
 0.985
ACS20796.1
PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: mms:mma_0314 methyl-accepting chemotaxis protein.
 
 0.985
ACS20797.1
PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: dia:Dtpsy_3481 methyl-accepting chemotaxis sensory transducer.
 
 0.985
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
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