node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS20950.1 | ACS20951.1 | Vapar_4339 | Vapar_4340 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | KEGG: pol:Bpro_1298 hypothetical protein. | 0.816 |
ACS20950.1 | ACS20954.1 | Vapar_4339 | Vapar_4343 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | KEGG: pol:Bpro_1295 putative lipoprotein. | 0.610 |
ACS20950.1 | ispE | Vapar_4339 | Vapar_4344 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.700 |
ACS20950.1 | ligA | Vapar_4339 | Vapar_2950 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.409 |
ACS20950.1 | mutM | Vapar_4339 | Vapar_4341 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.836 |
ACS20950.1 | nth | Vapar_4339 | Vapar_2571 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.512 |
ACS20950.1 | polA | Vapar_4339 | Vapar_1542 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.461 |
ACS20951.1 | ACS20950.1 | Vapar_4340 | Vapar_4339 | KEGG: pol:Bpro_1298 hypothetical protein. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.816 |
ACS20951.1 | ACS20954.1 | Vapar_4340 | Vapar_4343 | KEGG: pol:Bpro_1298 hypothetical protein. | KEGG: pol:Bpro_1295 putative lipoprotein. | 0.592 |
ACS20951.1 | ispE | Vapar_4340 | Vapar_4344 | KEGG: pol:Bpro_1298 hypothetical protein. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.481 |
ACS20951.1 | mutM | Vapar_4340 | Vapar_4341 | KEGG: pol:Bpro_1298 hypothetical protein. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.624 |
ACS20954.1 | ACS20950.1 | Vapar_4343 | Vapar_4339 | KEGG: pol:Bpro_1295 putative lipoprotein. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.610 |
ACS20954.1 | ACS20951.1 | Vapar_4343 | Vapar_4340 | KEGG: pol:Bpro_1295 putative lipoprotein. | KEGG: pol:Bpro_1298 hypothetical protein. | 0.592 |
ACS20954.1 | ispE | Vapar_4343 | Vapar_4344 | KEGG: pol:Bpro_1295 putative lipoprotein. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.888 |
ACS20954.1 | mutM | Vapar_4343 | Vapar_4341 | KEGG: pol:Bpro_1295 putative lipoprotein. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.635 |
ACS21462.1 | mutM | Vapar_4858 | Vapar_4341 | PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: dac:Daci_3045 DEAD/DEAH box helicase domain-containing protein. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.830 |
ACS21462.1 | uvrC | Vapar_4858 | Vapar_1783 | PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: dac:Daci_3045 DEAD/DEAH box helicase domain-containing protein. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.552 |
coaE | ispE | Vapar_4223 | Vapar_4344 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.409 |
coaE | mutM | Vapar_4223 | Vapar_4341 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.884 |
coaE | nth | Vapar_4223 | Vapar_2571 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.550 |