| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACS17920.1 | ACS20059.1 | Vapar_1269 | Vapar_3442 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: aav:Aave_3449 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.732 |
| ACS17920.1 | ACS20980.1 | Vapar_1269 | Vapar_4369 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: aav:Aave_3449 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase putative; KEGG: dac:Daci_1802 methyltransferase. | 0.441 |
| ACS17920.1 | coaD | Vapar_1269 | Vapar_4368 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: aav:Aave_3449 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.767 |
| ACS17920.1 | coaE | Vapar_1269 | Vapar_4223 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: aav:Aave_3449 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.619 |
| ACS17920.1 | guaA | Vapar_1269 | Vapar_2764 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: aav:Aave_3449 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.430 |
| ACS17920.1 | nadD | Vapar_1269 | Vapar_2686 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: aav:Aave_3449 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.559 |
| ACS20059.1 | ACS17920.1 | Vapar_3442 | Vapar_1269 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: aav:Aave_3449 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.732 |
| ACS20059.1 | coaD | Vapar_3442 | Vapar_4368 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.958 |
| ACS20059.1 | coaE | Vapar_3442 | Vapar_4223 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.618 |
| ACS20059.1 | coaX | Vapar_3442 | Vapar_4947 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.945 |
| ACS20059.1 | guaA | Vapar_3442 | Vapar_2764 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.566 |
| ACS20059.1 | nadD | Vapar_3442 | Vapar_2686 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.410 |
| ACS20939.1 | coaD | Vapar_4328 | Vapar_4368 | PFAM: domain of unknown function DUF1732; YicC domain protein; KEGG: rfr:Rfer_1626 hypothetical protein. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.755 |
| ACS20939.1 | guaA | Vapar_4328 | Vapar_2764 | PFAM: domain of unknown function DUF1732; YicC domain protein; KEGG: rfr:Rfer_1626 hypothetical protein. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.403 |
| ACS20977.1 | ACS20978.1 | Vapar_4366 | Vapar_4367 | KEGG: bte:BTH_I0229 UreA amidolyase-related protein; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2. | PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: rso:RSc2171 hypothetical protein. | 0.999 |
| ACS20977.1 | ACS20980.1 | Vapar_4366 | Vapar_4369 | KEGG: bte:BTH_I0229 UreA amidolyase-related protein; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2. | TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase putative; KEGG: dac:Daci_1802 methyltransferase. | 0.644 |
| ACS20977.1 | coaD | Vapar_4366 | Vapar_4368 | KEGG: bte:BTH_I0229 UreA amidolyase-related protein; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.795 |
| ACS20978.1 | ACS20977.1 | Vapar_4367 | Vapar_4366 | PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: rso:RSc2171 hypothetical protein. | KEGG: bte:BTH_I0229 UreA amidolyase-related protein; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2. | 0.999 |
| ACS20978.1 | ACS20980.1 | Vapar_4367 | Vapar_4369 | PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: rso:RSc2171 hypothetical protein. | TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase putative; KEGG: dac:Daci_1802 methyltransferase. | 0.644 |
| ACS20978.1 | coaD | Vapar_4367 | Vapar_4368 | PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: rso:RSc2171 hypothetical protein. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.779 |