close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS21031.1KEGG: hch:HCH_10017 hypothetical protein. (127 aa)    
Predicted Functional Partners:
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
 
     0.851
ACS21032.1
PFAM: protein of unknown function UPF0027; KEGG: pna:Pnap_0498 hypothetical protein.
 
     0.850
ACS21033.1
PFAM: band 7 protein; SMART: band 7 protein; KEGG: pol:Bpro_1471 band 7 protein.
 
     0.736
ACS17929.1
PFAM: peptidase M48 Ste24p; KEGG: pol:Bpro_3806 peptidase M48, Ste24p.
  
     0.623
ACS18010.1
KEGG: dac:Daci_5313 hypothetical protein.
  
     0.591
ACS20155.1
KEGG: ypg:YpAngola_A3877 hypothetical protein.
  
     0.543
ACS17556.1
PFAM: protein of unknown function DUF945; KEGG: dac:Daci_4282 hypothetical protein.
  
     0.538
ACS20383.1
KEGG: pol:Bpro_1598 hypothetical protein.
  
     0.531
ACS21916.1
Putative membrane protein involved in toxin uptake; KEGG: dac:Daci_2082 hypothetical protein.
  
     0.528
ACS22531.1
TIGRFAM: outer membrane adhesin like proteiin; PFAM: Hemolysin-type calcium-binding region; KEGG: dar:Daro_3199 VCBS.
  
     0.501
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.