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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS21034.1Sigma 54 interacting domain protein; PFAM: regulator of RNA terminal phosphate cyclase; sigma-54 factor interaction domain-containing protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: dac:Daci_0675 regulator of RNA terminal phosphate cyclase. (537 aa)    
Predicted Functional Partners:
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
 
  
 0.858
ACS21032.1
PFAM: protein of unknown function UPF0027; KEGG: pna:Pnap_0498 hypothetical protein.
 
   
 0.810
ACS21035.1
PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: bpe:BP1505 ornithine cyclodeaminase.
       0.651
ACS17129.1
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.623
ACS21264.1
PFAM: alpha/beta hydrolase fold; KEGG: pfl:PFL_6196 hypothetical protein.
  
     0.508
ACS22848.1
TIGRFAM: cytidyltransferase-related domain protein; PFAM: NUDIX hydrolase; cytidylyltransferase; KEGG: pna:Pnap_3717 cytidyltransferase-like protein.
  
     0.461
ACS21265.1
PFAM: Dual specificity protein phosphatase; KEGG: smt:Smal_3658 putative dual specificity phosphatase.
  
     0.447
ACS22796.1
PFAM: VWA containing CoxE family protein; SMART: von Willebrand factor type A; KEGG: pmr:PMI0558 hypothetical protein.
  
     0.427
ACS22793.1
PFAM: ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: pmr:PMI0560 ATPase.
  
     0.424
ACS21036.1
Hypothetical protein.
       0.416
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
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