close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS21201.1KEGG: ppd:Ppro_0239 hypothetical protein. (893 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.868
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.851
ACS21202.1
PFAM: helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: aav:Aave_0157 helicase domain-containing protein.
     
 0.810
ACS21200.1
KEGG: bpt:Bpet4235 hypothetical protein.
       0.803
ACS21199.1
PFAM: protein of unknown function DUF262; protein of unknown function DUF1524 RloF; KEGG: dol:Dole_2238 hypothetical protein.
       0.784
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.774
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.774
ACS21203.1
TIGRFAM: DNA binding domain protein, excisionase family; KEGG: aav:Aave_0156 DNA binding domain-containing protein.
       0.773
ACS21198.1
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: mgm:Mmc1_0787 site-specific DNA-methyltransferase (adenine-specific).
       0.688
ACS21197.1
PFAM: type III restriction protein res subunit; KEGG: dac:Daci_4204 type III restriction protein res subunit.
       0.686
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.