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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS21420.12-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; NADP oxidoreductase coenzyme F420-dependent; KEGG: dia:Dtpsy_0409 3-hydroxyisobutyrate dehydrogenase. (302 aa)    
Predicted Functional Partners:
ACS20568.1
TIGRFAM: glyoxylate carboligase; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; KEGG: psa:PST_3114 glyoxylate carboligase; Belongs to the TPP enzyme family.
  
 
 0.934
ACS20569.1
KEGG: dac:Daci_2118 hydroxypyruvate isomerase; TIGRFAM: hydroxypyruvate isomerase; PFAM: Xylose isomerase domain protein TIM barrel; Belongs to the hyi family.
 
 
 0.925
ACS19955.1
2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: xau:Xaut_2433 2-hydroxy-3-oxopropionate reductase.
  
  
 
0.924
ACS20570.1
KEGG: mpt:Mpe_A0975 2-hydroxy-3-oxopropionate reductase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; NADP oxidoreductase coenzyme F420-dependent.
  
  
 
0.917
ACS20535.1
Hydroxypyruvate reductase; PFAM: MOFRL domain protein; KEGG: ajs:Ajs_1122 hydroxypyruvate reductase.
    
 0.909
ACS18424.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: pna:Pnap_1622 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
    
 0.905
ACS21322.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: aav:Aave_4350 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
    
  0.901
ACS21833.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: pol:Bpro_0422 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
    
  0.901
ACS22222.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pol:Bpro_0053 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
    
  0.901
ACS21419.1
TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: pol:Bpro_0395 twitching motility protein.
       0.665
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
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