STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AM2010_2Molybdopterin biosynthesis protein MoeB; Pfam:pfam00899 ThiF family. (259 aa)    
Predicted Functional Partners:
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.998
AKM07440.1
Molybdopterin synthase sulfur carrier subunit; Pfam:pfam02597 ThiS family.
  
 0.985
AKM07241.1
Pfam:pfam00266 Aminotransferase class-V.
 
 
 0.974
AKM07242.1
Cysteine desulfurase; Pfam:pfam00266 Aminotransferase class-V.
 
 
 0.973
AKM07439.1
Molybdopterin converting factor; Pfam:pfam02391 MoaE protein.
 
 0.952
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.871
AKM06424.1
Peptidase; Pfam:pfam14464 Prokaryotic homologs of the JAB domain.
 
 0.814
AKM07518.1
Hypothetical protein.
   
   0.804
thiE
Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.762
AKM06858.1
Thioredoxin reductase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase.
  
    0.747
Your Current Organism:
Altererythrobacter marensis
NCBI taxonomy Id: 543877
Other names: A. marensis, Altererythrobacter marensis Seo and Lee 2010, Altererythrobacter sp. MSW-14, DSM 21428, KCTC 22370, strain MSW-14
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