node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKM06699.1 | AKM08551.1 | AM2010_614 | AM2010_2496 | Pfam:pfam00206 Lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 5''''-nucleotidase; Pfam:pfam02872 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | 0.919 |
AKM06699.1 | apt | AM2010_614 | AM2010_2124 | Pfam:pfam00206 Lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.963 |
AKM06699.1 | guaA | AM2010_614 | AM2010_2503 | Pfam:pfam00206 Lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.925 |
AKM06699.1 | guaB | AM2010_614 | AM2010_572 | Pfam:pfam00206 Lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.917 |
AKM06699.1 | purA | AM2010_614 | AM2010_1249 | Pfam:pfam00206 Lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.996 |
AKM06699.1 | purH | AM2010_614 | AM2010_2309 | Pfam:pfam00206 Lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Bifunctional purine biosynthesis protein PurH; Pfam:pfam01808 AICARFT/IMPCHase bienzyme. | 0.992 |
AKM06699.1 | surE | AM2010_614 | AM2010_272 | Pfam:pfam00206 Lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.929 |
AKM06699.1 | tmk | AM2010_614 | AM2010_952 | Pfam:pfam00206 Lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.450 |
AKM08551.1 | AKM06699.1 | AM2010_2496 | AM2010_614 | 5''''-nucleotidase; Pfam:pfam02872 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | Pfam:pfam00206 Lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.919 |
AKM08551.1 | AKM08707.1 | AM2010_2496 | AM2010_2652 | 5''''-nucleotidase; Pfam:pfam02872 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.931 |
AKM08551.1 | apt | AM2010_2496 | AM2010_2124 | 5''''-nucleotidase; Pfam:pfam02872 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.929 |
AKM08551.1 | guaA | AM2010_2496 | AM2010_2503 | 5''''-nucleotidase; Pfam:pfam02872 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.931 |
AKM08551.1 | guaB | AM2010_2496 | AM2010_572 | 5''''-nucleotidase; Pfam:pfam02872 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.931 |
AKM08551.1 | purA | AM2010_2496 | AM2010_1249 | 5''''-nucleotidase; Pfam:pfam02872 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.924 |
AKM08551.1 | purH | AM2010_2496 | AM2010_2309 | 5''''-nucleotidase; Pfam:pfam02872 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | Bifunctional purine biosynthesis protein PurH; Pfam:pfam01808 AICARFT/IMPCHase bienzyme. | 0.916 |
AKM08551.1 | surE | AM2010_2496 | AM2010_272 | 5''''-nucleotidase; Pfam:pfam02872 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.917 |
AKM08551.1 | tdk | AM2010_2496 | AM2010_1560 | 5''''-nucleotidase; Pfam:pfam02872 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | Pfam:pfam00265 Thymidine kinase. | 0.917 |
AKM08551.1 | tmk | AM2010_2496 | AM2010_952 | 5''''-nucleotidase; Pfam:pfam02872 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.932 |
AKM08707.1 | AKM08551.1 | AM2010_2652 | AM2010_2496 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 5''''-nucleotidase; Pfam:pfam02872 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | 0.931 |
AKM08707.1 | guaA | AM2010_2652 | AM2010_2503 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.438 |