STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBNAD-dependent protein deacylase; Pfam:pfam02146 Sir2 family; Belongs to the sirtuin family. Class III subfamily. (235 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 0.951
nadD
Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.935
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.920
AKM07347.1
NAD(P) transhydrogenase subunit alpha; Pfam:pfam01262 Alanine dehydrogenase/PNT, C-terminal domain.
     
 0.909
AKM07536.1
Pfam:pfam00293 NUDIX domain.
    
 0.909
AKM07346.1
Pyridine nucleotide transhydrogenase; Pfam:pfam12769 Domain of unknown function (DUF3814).
     
 0.905
AKM07345.1
Pfam:pfam02233 NAD(P) transhydrogenase beta subunit.
    
  0.901
AKM07035.1
Nucleoside triphosphate hydrolase; Pfam:pfam03819 MazG nucleotide pyrophosphohydrolase domain.
    
  0.901
AKM07313.1
Pfam:pfam00850 Histone deacetylase domain.
    
 
 0.771
AKM08506.1
DNA helicase; Pfam:pfam00270 DEAD/DEAH box helicase.
  
 
 0.694
Your Current Organism:
Altererythrobacter marensis
NCBI taxonomy Id: 543877
Other names: A. marensis, Altererythrobacter marensis Seo and Lee 2010, Altererythrobacter sp. MSW-14, DSM 21428, KCTC 22370, strain MSW-14
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