STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKM06492.1Threonine dehydratase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. (417 aa)    
Predicted Functional Partners:
AKM06882.1
Pfam:pfam10369 Small subunit of acetolactate synthase.
  
 
 0.974
AKM07445.1
Pfam:pfam14821 Threonine synthase N terminus.
  
 
 0.952
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 
 0.950
AKM07731.1
Acetolactate synthase, large subunit; Pfam:pfam02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Belongs to the TPP enzyme family.
  
 0.936
AKM06883.1
Acetolactate synthase large subunit; Pfam:pfam02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain.
  
 0.936
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.935
AKM08554.1
Pfam:pfam03313 Serine dehydratase alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.927
AKM06863.1
Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme.
  
  
 
0.923
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 
 0.922
AKM08192.1
Threonine aldolase; Pfam:pfam01212 Beta-eliminating lyase.
  
 
 0.918
Your Current Organism:
Altererythrobacter marensis
NCBI taxonomy Id: 543877
Other names: A. marensis, Altererythrobacter marensis Seo and Lee 2010, Altererythrobacter sp. MSW-14, DSM 21428, KCTC 22370, strain MSW-14
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