STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (401 aa)    
Predicted Functional Partners:
AKM06513.1
Cysteine synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme.
 
 0.974
AKM06952.1
Cysteine synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.971
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.960
AKM08603.1
Pfam:pfam02574 Homocysteine S-methyltransferase.
  
 
 0.947
AKM07079.1
O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme.
 
 
0.938
AKM06545.1
Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme.
 
 
0.936
AKM06541.1
Sulfite reductase (NADPH) hemoprotein beta-component; Pfam:pfam01077 Nitrite and sulphite reductase 4Fe-4S domain.
  
 0.935
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
  
 0.931
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.925
AKM08605.1
5-methyltetrahydrofolate-homocysteine methyltransferase; Pfam:pfam00809 Pterin binding enzyme.
  
 
 0.925
Your Current Organism:
Altererythrobacter marensis
NCBI taxonomy Id: 543877
Other names: A. marensis, Altererythrobacter marensis Seo and Lee 2010, Altererythrobacter sp. MSW-14, DSM 21428, KCTC 22370, strain MSW-14
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.