STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKM07061.1Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (459 aa)    
Predicted Functional Partners:
AKM07136.1
2-oxoisovalerate dehydrogenase alpha subunit; Pfam:pfam00676 Dehydrogenase E1 component.
 0.999
AKM07727.1
Thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit; Pfam:pfam00676 Dehydrogenase E1 component.
 0.999
AKM07986.1
MFS transporter; Pfam:pfam00676 Dehydrogenase E1 component.
 
0.999
AKM06622.1
Dihydrolipoyl dehydrogenase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase.
 0.999
AKM07003.1
Dihydrolipoyl dehydrogenase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase.
 0.999
pdhA
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
AKM07086.1
Glutathione reductase (NADPH); Maintains high levels of reduced glutathione.
 
 0.998
AKM06625.1
Alpha-ketoglutarate decarboxylase; Pfam:pfam02779 Transketolase, pyrimidine binding domain.
  
 0.996
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.993
AKM08083.1
Pfam:pfam03949 Malic enzyme, NAD binding domain.
  
 
 0.991
Your Current Organism:
Altererythrobacter marensis
NCBI taxonomy Id: 543877
Other names: A. marensis, Altererythrobacter marensis Seo and Lee 2010, Altererythrobacter sp. MSW-14, DSM 21428, KCTC 22370, strain MSW-14
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