node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
D521_0132 | D521_1349 | D521_0132 | D521_1349 | Glutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily. | Iron-sulfur cluster assembly protein IscA; Belongs to the HesB/IscA family. | 0.599 |
D521_0132 | hscB | D521_0132 | D521_1348 | Glutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily. | Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.501 |
D521_1346 | D521_1349 | D521_1346 | D521_1349 | Ferredoxin, 2Fe-2S type, ISC system. | Iron-sulfur cluster assembly protein IscA; Belongs to the HesB/IscA family. | 0.953 |
D521_1346 | D521_1350 | D521_1346 | D521_1350 | Ferredoxin, 2Fe-2S type, ISC system. | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.991 |
D521_1346 | D521_1352 | D521_1346 | D521_1352 | Ferredoxin, 2Fe-2S type, ISC system. | BadM/Rrf2 family transcriptional regulator. | 0.558 |
D521_1346 | dnaK | D521_1346 | D521_1751 | Ferredoxin, 2Fe-2S type, ISC system. | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.519 |
D521_1346 | hscA | D521_1346 | D521_1347 | Ferredoxin, 2Fe-2S type, ISC system. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.963 |
D521_1346 | hscB | D521_1346 | D521_1348 | Ferredoxin, 2Fe-2S type, ISC system. | Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.988 |
D521_1346 | iscS | D521_1346 | D521_1351 | Ferredoxin, 2Fe-2S type, ISC system. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.966 |
D521_1349 | D521_0132 | D521_1349 | D521_0132 | Iron-sulfur cluster assembly protein IscA; Belongs to the HesB/IscA family. | Glutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.599 |
D521_1349 | D521_1346 | D521_1349 | D521_1346 | Iron-sulfur cluster assembly protein IscA; Belongs to the HesB/IscA family. | Ferredoxin, 2Fe-2S type, ISC system. | 0.953 |
D521_1349 | D521_1350 | D521_1349 | D521_1350 | Iron-sulfur cluster assembly protein IscA; Belongs to the HesB/IscA family. | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.969 |
D521_1349 | D521_1352 | D521_1349 | D521_1352 | Iron-sulfur cluster assembly protein IscA; Belongs to the HesB/IscA family. | BadM/Rrf2 family transcriptional regulator. | 0.743 |
D521_1349 | D521_2094 | D521_1349 | D521_2094 | Iron-sulfur cluster assembly protein IscA; Belongs to the HesB/IscA family. | BadM/Rrf2 family transcriptional regulator. | 0.549 |
D521_1349 | dnaK | D521_1349 | D521_1751 | Iron-sulfur cluster assembly protein IscA; Belongs to the HesB/IscA family. | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.513 |
D521_1349 | hscA | D521_1349 | D521_1347 | Iron-sulfur cluster assembly protein IscA; Belongs to the HesB/IscA family. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.866 |
D521_1349 | hscB | D521_1349 | D521_1348 | Iron-sulfur cluster assembly protein IscA; Belongs to the HesB/IscA family. | Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.970 |
D521_1349 | iscS | D521_1349 | D521_1351 | Iron-sulfur cluster assembly protein IscA; Belongs to the HesB/IscA family. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.944 |
D521_1349 | purC | D521_1349 | D521_1809 | Iron-sulfur cluster assembly protein IscA; Belongs to the HesB/IscA family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.668 |
D521_1350 | D521_1346 | D521_1350 | D521_1346 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Ferredoxin, 2Fe-2S type, ISC system. | 0.991 |