node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
D521_0192 | D521_0882 | D521_0192 | D521_0882 | 2-dehydropantoate 2-reductase. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.901 |
D521_0192 | panB | D521_0192 | D521_1749 | 2-dehydropantoate 2-reductase. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.915 |
D521_0192 | panC | D521_0192 | D521_0511 | 2-dehydropantoate 2-reductase. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.915 |
D521_0699 | panB | D521_0699 | D521_1749 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.682 |
D521_0699 | panC | D521_0699 | D521_0511 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.500 |
D521_0882 | D521_0192 | D521_0882 | D521_0192 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 2-dehydropantoate 2-reductase. | 0.901 |
D521_0882 | panB | D521_0882 | D521_1749 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.915 |
D521_0882 | panC | D521_0882 | D521_0511 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.915 |
D521_1488 | ilvD | D521_1488 | D521_0544 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.921 |
D521_1488 | ilvE | D521_1488 | D521_1813 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.961 |
D521_1488 | panB | D521_1488 | D521_1749 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.911 |
D521_1745 | D521_1748 | D521_1745 | D521_1748 | Chromosomal replication initiator, DnaA; Belongs to the DnaA family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.628 |
D521_1745 | panB | D521_1745 | D521_1749 | Chromosomal replication initiator, DnaA; Belongs to the DnaA family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.612 |
D521_1745 | pcnB | D521_1745 | D521_1747 | Chromosomal replication initiator, DnaA; Belongs to the DnaA family. | Poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.833 |
D521_1748 | D521_1745 | D521_1748 | D521_1745 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Chromosomal replication initiator, DnaA; Belongs to the DnaA family. | 0.628 |
D521_1748 | panB | D521_1748 | D521_1749 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.828 |
D521_1748 | panC | D521_1748 | D521_0511 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.439 |
D521_1748 | pcnB | D521_1748 | D521_1747 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.887 |
ilvD | D521_1488 | D521_0544 | D521_1488 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.921 |
ilvD | ilvE | D521_0544 | D521_1813 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.961 |