STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT54383.1ATP dependent DNA ligase domain/DNA ligase OB-like domain. (278 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.996
KRT54026.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.995
rapA
Superfamily II DNA or RNA helicase, SNF2 family; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
  
 0.961
KRT54017.1
D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase.
   
 0.958
KRT55427.1
DNA polymerase III, delta prime subunit.
   
 0.952
KRT55015.1
Exodeoxyribonuclease III.
 
 
 0.940
KRT56236.1
Caspase domain.
   
 0.932
KRT54918.1
AAA domain.
   
 0.931
KRT56242.1
Rad3-related DNA helicase.
   
 
 0.930
KRT54878.1
Superfamily II DNA or RNA helicase; Belongs to the peptidase S24 family.
  
 
 0.925
Your Current Organism:
endosymbiont of Ridgeia
NCBI taxonomy Id: 54398
Other names: Ridgeia piscesae endosymbiont, e. of Ridgeia piscesae, endosymbiont of Ridgeia piscesae
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