STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (265 aa)    
Predicted Functional Partners:
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 0.999
panD
L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
  
 0.990
KRT55067.1
Nicotinate-nucleotide pyrophosphorylase (carboxylating).
     0.757
KRT55504.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase.
  
 
 0.714
KRT56456.1
Hypothetical protein.
    
 0.694
KRT55077.1
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
     
 0.644
birA
birA, biotin-[acetyl-CoA-carboxylase] ligase region; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
  
 0.636
KRT55505.1
poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.608
KRT55684.1
Branched-chain amino acid aminotransferase, group I.
    
 0.587
KRT55430.1
Aminodeoxychorismate lyase apoprotein.
    
 0.574
Your Current Organism:
endosymbiont of Ridgeia
NCBI taxonomy Id: 54398
Other names: Ridgeia piscesae endosymbiont, e. of Ridgeia piscesae, endosymbiont of Ridgeia piscesae
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.