Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMD98423.1Glycerol transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family. (255 aa)    
Predicted Functional Partners:
glpK
Converts glycerol and ADP to glycerol-3-phosphate and ADP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FGGY kinase family.
 
 
 0.982
AMD98422.1
Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.951
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.761
AMD98972.1
Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.724
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
    
 
 0.724
AMD98967.1
AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.707
AME00196.1
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
   0.705
AMD98588.1
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.631
AMD98880.1
Cell division protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family.
    
   0.631
AMD98881.1
Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.631
Your Current Organism:
Actinomyces oris
NCBI taxonomy Id: 544580
Other names: A. oris, ATCC 27044, Actinomyces naeslundii genospecies 2, Actinomyces oris Henssge et al. 2009, CCUG 34288, DSM 23056, JCM 16131
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