STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCEG_03934Methylenetetrahydrofolate dehydrogenase. (339 aa)    
Predicted Functional Partners:
HCEG_03259
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 
 0.991
HCEG_01689
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.985
HCEG_01236
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.985
HCEG_05413
Phosphoribosylglycinamide formyltransferase.
  
 
 0.978
HCEG_04985
C-1-tetrahydrofolate synthase.
  
 
0.974
HCEG_00889
MTHFS protein.
    
 0.965
HCEG_04637
Glycine dehydrogenase.
  
 
 0.959
HCEG_07850
Thymidylate synthase.
  
 
 0.957
HCEG_00849
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
    
 0.953
HCEG_06263
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
    
 0.953
Your Current Organism:
Histoplasma capsulatum H88
NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.