STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCEG_05237Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (419 aa)    
Predicted Functional Partners:
HCEG_08622
Elongation factor Tu GTP binding domain-containing protein.
   
 
 0.990
HCEG_00763
Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
    
 
 0.944
HCEG_02209
ATP-binding cassette sub-family E member 1.
  
 
 0.930
HCEG_02454
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
    
 
 0.928
HCEG_00158
Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
 
 0.926
HCEG_04187
40S ribosomal protein S20.
    
 
 0.920
HCEG_07747
40S ribosomal protein S17.
    
 
 0.918
HCEG_00332
Uncharacterized protein.
    
 
 0.914
HCEG_04924
60S ribosomal protein.
   
   0.914
HCEG_01852
40S ribosomal protein S10.
    
 
 0.912
Your Current Organism:
Histoplasma capsulatum H88
NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.