STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCEG_06722DNA repair helicase rad5,16. (1113 aa)    
Predicted Functional Partners:
HCEG_02461
RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
    
 0.795
HCEG_04596
Chromatin remodeling complex subunit; Belongs to the actin family.
    
 0.778
HCEG_05498
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.766
HCEG_04597
Chromatin-remodeling complex subunit ies6.
    
 0.764
HCEG_07774
Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family.
    
  0.740
HCEG_00596
Serine/threonine protein kinase plo1.
   
 0.734
HCEG_03038
Postreplication repair E3 ubiquitin-protein ligase rad18.
   
 0.718
HCEG_04201
Exonuclease.
   
 0.713
HCEG_05468
DNA-directed RNA polymerase I.
    
 0.688
HCEG_02315
Ubiquitin-conjugating enzyme.
    
 0.687
Your Current Organism:
Histoplasma capsulatum H88
NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.