STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCEG_07464Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (700 aa)    
Predicted Functional Partners:
HCEG_02370
3-ketosteroid reductase.
   
 
 0.958
HCEG_04091
Squalene epoxidase.
 
 
 
 0.955
HCEG_05132
Cytochrome P450 sterol 14 alpha-demethylase; Belongs to the cytochrome P450 family.
   
 0.954
HCEG_09351
Serine/threonine protein kinase chk2; Belongs to the cytochrome P450 family.
   
 0.954
HCEG_08874
Cytochrome P450 sterol C-22 desaturase; Belongs to the cytochrome P450 family.
    
 0.952
HCEG_04710
C4-methylsterol oxidase; Belongs to the sterol desaturase family.
   
 
 0.943
HCEG_07513
C-5 sterol desaturase; Belongs to the sterol desaturase family.
   
 0.943
HCEG_04628
Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.
   
 0.932
HCEG_07868
Squalene synthetase.
  
 
 0.929
HCEG_00873
Ergosterol biosynthetic protein.
   
 
 0.921
Your Current Organism:
Histoplasma capsulatum H88
NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.