STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCEG_07564Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (420 aa)    
Predicted Functional Partners:
HCEG_05329
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
     
 0.953
HCEG_04177
Acetamidase.
   
 
  0.918
HCEG_05915
Malate dehydrogenase.
  
 0.811
HCEG_07504
Malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.811
HCEG_09070
Malate synthase; Belongs to the malate synthase family.
   
 
 0.803
HCEG_08359
3-hydroxyisobutyrate dehydrogenase.
  
 
 0.801
HCEG_01187
Malic enzyme.
    
 0.783
HCEG_01961
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.778
HCEG_08802
Tryptophan synthase.
    
  0.777
HCEG_08250
Fumarate hydratase class II.
  
 
 0.763
Your Current Organism:
Histoplasma capsulatum H88
NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.