STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCDG_02317Methyltransferase. (331 aa)    
Predicted Functional Partners:
HCDG_03720
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.669
HCDG_05521
Squalene synthetase.
    
 0.666
HCDG_00438
Bystin.
   
  0.664
HCDG_08216
Low temperature viability protein ltv1.
   
  0.651
HCDG_04879
20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.
   
  0.649
HCDG_05497
Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.
    
 0.646
HCDG_05940
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
   
  0.646
HCDG_07132
37S ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.
    
 0.646
HCDG_03631
40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.
    
  0.644
RPS1
40S ribosomal protein S1; Belongs to the eukaryotic ribosomal protein eS1 family.
    
  0.644
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.