STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCDG_04256WD repeat protein. (761 aa)    
Predicted Functional Partners:
HCDG_02733
Glucosamine 6-phosphate synthetase.
  
 
 0.977
HCDG_01906
N-acetyl-gamma-glutamyl-phosphate reductase; In the N-terminal section; belongs to the acetylglutamate kinase family.
  
 0.956
NCS2
Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.
    
   0.947
HCDG_07867
Histidine biosynthesis trifunctional protein.
  
 
 0.896
HCDG_03701
Argininosuccinate synthetase.
  
 0.873
HCDG_02245
Allantoinase.
  
 
 0.824
HCDG_06263
Orotate reductase.
  
 0.822
HCDG_00726
Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
    
 0.808
HCDG_01626
Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
    
 0.764
HCDG_09319
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
  
 
 0.718
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.